Endocrine Abstracts

Tc- 99m Sestamibi parathyroid scan (SP scan) is performed to identify location of either hyperplastic or adenomatous gland(s) in primary hyperparathyroidism (HPT). In this study we evaluated diagnostic outcome in 55 consecutive patients with clinical diagnosis of HPT who were referred for SP scans and subsequently had parathyroid surgery. These patients with HPT were of 66.9+12.46 (mean + SD) age, and had serum calcium 10.9+0.93 mg/dl, phosphorus 3.0+0.51 mg/dl, chloride 107+3...

Vasopressin release is stimulated following the administration of 3,4-methylenedioxymethamphetamine (MDMA ) in man. MDMA and a major metabolite, 4-hydroxy-3-methoxymethamphetamine (HMMA), have also been shown to stimulate neurohypophysial hormone release in vitro. A study has now been performed comparing the response to four other metabolites with the parent compound. Hypothalami obtained from male Wistar rats were exposed to medium alone (B1) and the medium containing ...